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Dove focuses on providing supplements that are necessary for Dr Rind’s Metabolic Therapy™ - correction of adrenal and thyroid dysfunction. Our mission at Dove is to give our customers an easy way to buy quality supplements at a good price. Please feel free to contact us with any questions or comments.
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Pregnenolone by Amni Douglas Labs
Pregnenolone - 25 mg 60 tablets sublingual Pregnenolone may be helpful for supporting adrenal function and anxiety. NOTE FROM DR. RIND Pregnenolone is a precursor to many of the hormones produced by the adrenal glands. It is a raw material that supports basic adrenal function. Pregnenolone is best taken towards the evening but may be taken earlier if it interferes with sleep. The usual dose is 25 mg. Pregnenolone is often referred to as the grandparent precursor to steroid hormones in mammals. Pregnenolone is synthesized from cholesterol in the mitochondria of adrenal glands. Pregnenolone is also made to a lesser extent in the brain, liver, skin, testes and ovaries. Once synthesized, pregnenolone is released from the mitochondria into the cytosol where it can be converted to DHEA (dehydroepiandrosterone) or to progesterone. DHEA serves as a precursor compound to the androgens and the estrogens through androstenedione as the intermediate compound. Progesterone is the precursor to cortisol, aldosterone, androstenedione, estrogen, and testosterone. Pregnenolone may also be secreted directly into the blood where it circulates primarily as the sulfated form. Pregnenolone has many actions of its own not attributable to its conversion to progesterone or to DHEA. Recent studies show that pregnenolone is important for the function of brain, nervous tissue, liver, pancreas, reproductive tissues, pituitary and skin. Pregnenolone is found in higher concentrations in the central nervous system compared to the peripheral tissues which may reflect its importance in brain function. As with many hormones, pregnenolone production declines with age. It is estimated that pregnenolone production is about 60% less at age 75 than at age 35. Pregnenolone levels may also decline under various conditions of physiological stress, such as acute and chronic infections and trauma.
INGREDIENTS Pregnenolone (3-alphahydroxy-5-beta-pregnen-20-one)..............25 mg
STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.
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25 mg 60 caps